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KMID : 1039220220320020102
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Journal of Korean Society of Occupational and Environmental Hygiene
2022 Volume.32 No. 2 p.102 ~ p.110
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Concentrations of N,N-dimethylformamide in Polyurethane Gloves and Risk Assessment for Dermal Exposures
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Park Hae-Dong
Ro Ji-Won
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Abstract
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Objectives: The purpose of this study is to analyze the content of N,N-dimethylformamide(DMF) in polyurethane coated gloves(PU-gloves) and to assess the dermal exposure generated by wearing them.
Methods: We analyzed the concentrations of DMF in 12 gloves by EN16778 standard. The samples cut into pieces of about 10 by 10 mm and extracted with methanol in flask in an ultrasonic bath at 70℃. An aliquot of the extract is analyzed with GC-MS. The dose of dermal exposure was calculated by ECETOC TRA consumer 3.1 and compared with derived no effect level(DNEL) for systemic effects due to long term exposure by workers. The extracted amount of DMF by saline solution was compared with that by EN16778 standard.
Results: The mean concentration of DMF in PU-gloves was 1,377 ㎎/㎏(range 13~3,948 ㎎/㎏). The concentration of DMF showed significantly differences by packing type, manufacturer, and price(p<0.05). The dose of dermal exposure was 0.0007~0.572 ㎎/㎏ body weight/day when the DMF content was 10~4,000 ㎎/㎏. The DMF extracted by saline solution was around 11% for 8 hours.
Conclusions: The risk of dermal exposure due to the residual DMF in the PU-gloves was not signifiant. But, the limit of 1,000 ㎎/㎏ in PU-gloves can be recommended for international standard and trading systems.
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KEYWORD
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N, N-dimethylformamide, DMF, polyurethane, glove, derived no effect level
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